- gla (Scottish Gaelic language (ISO 639-2 code))
- GLAAD (Gay and Lesbian Alliance Against Defamation)
- GLAC (General Ledger Accounting Code)
- GLACURH (Great Lake Affiliation of College and University Residence Halls)
- GLAD (Garbage, Laundry, And Dishes)
- GLAP (Greenfire Landowner Awareness Patrol)
- GLASS (Gay Lesbian And Straight Spectrum)
- GLAST (Gamma-ray Large Area Space Telescope)
- GLATGM (Gun Launched Anti-Tank Guided Missile)
- GLB (Good Life Broadcasting)
- GLBA (Gramm-Leach-Bliley Act)
- GLBI (Good Life Broadcasting, Inc.)
- glbl (Great Lakes Baseball League)
- GLBT (Gay, Lesbian, Bisexual and Transgender)
- GLBTIQ (Gay, Lesbian, Bisexual, Transgender, Intersex and Queer)
- GLBTQ (Gay, Lesbian, Bisexual, Trangendered and Questioning)
- GLC (gun lay computer)
- GLCEC (Guiding Light Christian Educational Center)
- GLCF (Great Lakes Center Foundation)
- GLCM (Ground Launched Cruise Missile)
- GLCP (Good Life Cycle Practice)
- GLCP INC. (Guiding Light Christian Partnership Inc.)
- GLD (Goodland Municipal Airport (Renner Field))
- GLDF (Generator to Load Distribution Factor. See Load balancing (electricity))
- GLDNSM (Grenade Launcher Day-Night Sight Mount)
- gle (Irish language (ISO 639-2 code))