- GL(Graphics Library)
- Gl.(Gloria ("Glory to God", etc.))
- gla(Scottish Gaelic language (ISO 639-2 code))
- GLAAD(Gay and Lesbian Alliance Against Defamation)
- GLAC(General Ledger Accounting Code)
- GLACURH(Great Lake Affiliation of College and University Residence Halls)
- GLAD(Garbage, Laundry, And Dishes)
- GLAP(Greenfire Landowner Awareness Patrol)
- GLASS(Gay Lesbian And Straight Spectrum)
- GLAST(Gamma-ray Large Area Space Telescope)
- GLATGM(Gun Launched Anti-Tank Guided Missile)
- GLB(Good Life Broadcasting)
- GLBA(Gramm-Leach-Bliley Act)
- GLBI(Good Life Broadcasting, Inc.)
- glbl(Great Lakes Baseball League)
- GLBT(Gay, Lesbian, Bisexual and Transgender)
- GLBTIQ(Gay, Lesbian, Bisexual, Transgender, Intersex and Queer)
- GLBTQ(Gay, Lesbian, Bisexual, Trangendered and Questioning)
- GLC(gun lay computer)
- GLCEC(Guiding Light Christian Educational Center)
- GLCF(Great Lakes Center Foundation)
- GLCM(Ground Launched Cruise Missile)
- GLCP(Good Life Cycle Practice)
- GLCP INC.(Guiding Light Christian Partnership Inc.)
- GLD(Goodland Municipal Airport (Renner Field))
- GLDF(Generator to Load Distribution Factor. See Load balancing (electricity))
- GLDNSM(Grenade Launcher Day-Night Sight Mount)